Satellite cell depletion in degenerative skeletal muscle
نویسندگان
چکیده
منابع مشابه
Satellite cell depletion prevents fiber hypertrophy in skeletal muscle.
The largest mammalian cells are the muscle fibers, and they have multiple nuclei to support their large cytoplasmic volumes. During hypertrophic growth, new myonuclei are recruited from satellite stem cells into the fiber syncytia, but it was recently suggested that such recruitment is not obligatory: overload hypertrophy after synergist ablation of the plantaris muscle appeared normal in trans...
متن کاملSatellite Cell Proliferation in Adult Skeletal Muscle
England et al. (1990), Very mild muscular dystrophy associated with the deletion of 46% of dystrophin., Nature, 343:180-182. Gilboa et al. (1986), Transfer and Expression of Cloned Genes Using Retroviral Vectors., Biotechniques, 4(6):5O4-5 12. Allbrook, D. (1981), Skeletal Muscle Regeneration, Muscle and Nerve, 4:234-245. Ishiura et al. (1986), Biochemical Aspects of Bupivacaine-Induced Acute M...
متن کاملSatellite Cell of Skeletal Muscle Fibers
In the course of an electron microscopic study of the peripheral region of the skeletal muscle fiber of the frog, the presence of certain cells, intimately associated with the muscle fiber, have been observed which we have chosen to call satellite cells. Since these cells have not been reported previously and indeed might be of interest to students of muscle histology and furthermore, as we sha...
متن کاملSatellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy.
Resident muscle stem cells, known as satellite cells, are thought to be the main mediators of skeletal muscle plasticity. Satellite cells are activated, replicate, and fuse into existing muscle fibers in response to both muscle injury and mechanical load. It is generally well-accepted that satellite cells participate in postnatal growth, hypertrophy, and muscle regeneration following injury; ho...
متن کاملFunctional Overload Enhances Satellite Cell Properties in Skeletal Muscle
Skeletal muscle represents a plentiful and accessible source of adult stem cells. Skeletal-muscle-derived stem cells, termed satellite cells, play essential roles in postnatal growth, maintenance, repair, and regeneration of skeletal muscle. Although it is well known that the number of satellite cells increases following physical exercise, functional alterations in satellite cells such as proli...
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ژورنال
عنوان ژورنال: Apoptosis
سال: 2003
ISSN: 1360-8185
DOI: 10.1023/a:1026127307457